Compound Detail
CHEMBL293798
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL293798 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IXRCJYBQPZJHRZ-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
195.2
MW (Da)
1.44
ALogP
3
HBA
1
HBD
76.7
PSA (Ų)
0.50
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 5.3 | 5.3 | 5000.0 | 1 |
| Protein kinase Pfmrk CHEMBL4090 | IC50 | 5.29 | 5.29 | 5100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 5000.0 | nM | 5.3 | Antimicrobial activity against Plasmodium falciparum | 20185316 |
| Protein kinase Pfmrk | IC50 | = | 5100.0 | nM | 5.29 | Inhibitory activity against Plasmodium falciparum cyclin dependent protein kinas... | 12930149 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1676428 | 10.1021/jm00110a022 | Epidermal growth factor receptor | 1 |
| 12930149 | 10.1021/jm0300983 | Protein kinase Pfmrk | 1 |
| 1479375 | 10.1021/np50089a001 | Epidermal growth factor receptor | 1 |
| 20185316 | 10.1016/j.bmc.2010.01.068 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine