Compound Detail
CHEMBL294186
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL294186 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JJXGGSUCGLJFTO-PXNSSMCTSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
309.4
MW (Da)
3.34
ALogP
3
HBA
1
HBD
32.7
PSA (Ų)
0.88
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(1A) dopamine receptor CHEMBL265 | Ki | 5.38 | 5.38 | 4197.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | Ki | = | 4197.0 | nM | 5.38 | Inhibition of [3H]SCH-23390 binding to rat striatal homogenate dopamine receptor... | 2666667 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2666667 | 10.1021/jm00128a038 | D(1A) dopamine receptor | 1 |
| 2666667 | 10.1021/jm00128a038 | D(2) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine