Compound Detail
CHEMBL29634
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL29634 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MRGUIJVNFRTRSF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
259.2
MW (Da)
0.32
ALogP
3
HBA
4
HBD
120.8
PSA (Ų)
0.56
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.08
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | IC50 | 5.08 | 5.08 | 8400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | IC50 | = | 8400.0 | nM | 5.08 | Ability to displace [3H]CPP from NMDA receptor in rat brain membrane | 1533422 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1386112 | 10.1021/jm00092a005 | Mus musculus | 2 |
| 1533422 | 10.1021/jm00086a004 | Glutamate NMDA receptor | 1 |
| 18462943 | 10.1016/j.bmc.2008.04.015 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine