Compound Detail
CHEMBL299511
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Basic Information
| ChEMBL ID | CHEMBL299511 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DAKLNHHLHPIOPS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
229.3
MW (Da)
2.27
ALogP
3
HBA
3
HBD
66.5
PSA (Ų)
0.71
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| D(1A) dopamine receptor CHEMBL265 | Ki | 5.82 | 5.82 | 1500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| D(1A) dopamine receptor | Ki | = | 1500.0 | nM | 5.82 | Displacement of [3H]fenoldopam from Dopamine receptor D1 of rat striatum membran... | 3761310 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3761310 | 10.1021/jm00160a018 | D(1A) dopamine receptor | 1 |
| 3761310 | 10.1021/jm00160a018 | D(2) dopamine receptor | 1 |
Data from ChEMBL 36 via Core Engine