Compound Detail
CHEMBL302622
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL302622 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BRHWTDLTWBCPDW-HNNXBMFYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
351.7
MW (Da)
3.68
ALogP
2
HBA
2
HBD
54.0
PSA (Ų)
0.71
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase CHEMBL247 | IC50 | 6.89 | 6.89 | 129.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase | IC50 | = | 129.0 | nM | 6.89 | Inhibition of HIV-1 reverse transcriptase. | 10821714 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10821714 | 10.1021/jm990580e | Human immunodeficiency virus 1 | 4 |
| 10821714 | 10.1021/jm990580e | Human immunodeficiency virus type 1 reverse transcriptase | 2 |
Data from ChEMBL 36 via Core Engine