Compound Detail
CHEMBL30323
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Basic Information
| ChEMBL ID | CHEMBL30323 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MOBZTQHHLZEMJU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
314.7
MW (Da)
4.24
ALogP
5
HBA
2
HBD
80.1
PSA (Ų)
0.56
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.49
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 5.49 | 5.49 | 3260.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 3260.0 | nM | 5.49 | Antiplasmodial activity against Plasmodium falciparum K1 | 37163950 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10888320 | 10.1016/s0960-894x(00)00255-9 | Mus musculus | 3 |
| - | 10.1016/S0960-894X(97)10074-9 | NADH-cytochrome b5 reductase | 3 |
| - | 10.1016/S0960-894X(97)10074-9 | Canis familiaris | 2 |
| 37163950 | 10.1016/j.ejmech.2023.115458 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine