Compound Detail
CHEMBL303639
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL303639 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WEQSXWDPPMOIEJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
421.4
MW (Da)
4.42
ALogP
6
HBA
0
HBD
50.1
PSA (Ų)
0.57
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.84
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL1800 | Ki | 6.84 | 6.84 | 145.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 145.0 | nM | 6.84 | Displacement of [125I]-sauvagine from Corticotropin releasing factor receptor 1 ... | 12127521 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12127521 | 10.1016/s0960-894x(02)00358-x | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine