Compound Detail
CHEMBL306838
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Basic Information
| ChEMBL ID | CHEMBL306838 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNAIFLPGGYQDGD-CQSZACIVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
335.4
MW (Da)
2.11
ALogP
5
HBA
3
HBD
71.0
PSA (Ų)
0.61
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-3 adrenergic receptor CHEMBL246 | EC50 | 5.1 | 5.1 | 7900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-3 adrenergic receptor | EC50 | = | 7900.0 | nM | 5.1 | Agonist efficacy for human Beta-3 adrenergic receptor expressed in chinese hamst... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(96)00603-8 | Beta-3 adrenergic receptor | 2 |
Data from ChEMBL 36 via Core Engine