Compound Detail
CHEMBL30853
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Basic Information
| ChEMBL ID | CHEMBL30853 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VYOAJPJWGUBAGB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
116.1
MW (Da)
-0.85
ALogP
3
HBA
2
HBD
52.6
PSA (Ų)
0.41
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 CHEMBL330 | IC50 | 4.11 | 4.11 | 78000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, NMDA 1 | IC50 | = | 78000.0 | nM | 4.11 | In vitro inhibitory activity to inhibit [3H]glycine binding to NMDA receptor | 10360746 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10360746 | 10.1016/s0960-894x(99)00194-8 | Glutamate receptor ionotropic, NMDA 1 | 1 |
Data from ChEMBL 36 via Core Engine