Compound Detail
CHEMBL308967
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Basic Information
| ChEMBL ID | CHEMBL308967 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OGWVDDMVJFIRKE-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
403.6
MW (Da)
6.24
ALogP
2
HBA
1
HBD
40.5
PSA (Ų)
0.44
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Retinoic acid receptor gamma CHEMBL2003 | EC50 | 6.58 | 6.58 | 260.0 | 1 |
| Retinoic acid receptor beta CHEMBL2008 | EC50 | 6.55 | 6.55 | 280.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Retinoic acid receptor gamma | EC50 | = | 260.0 | nM | 6.58 | Transactivation potency for Retinoic acid receptor gamma | - |
| Retinoic acid receptor beta | EC50 | = | 280.0 | nM | 6.55 | Transactivation potency for Retinoic acid receptor beta | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(97)00435-6 | Retinoic acid receptor alpha | 2 |
| - | 10.1016/S0960-894X(97)00435-6 | Retinoic acid receptor beta | 2 |
| - | 10.1016/S0960-894X(97)00435-6 | Retinoic acid receptor gamma | 2 |
Data from ChEMBL 36 via Core Engine