Compound Detail
CHEMBL311104
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Basic Information
| ChEMBL ID | CHEMBL311104 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OVTYRSXQQLOYOY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
356.3
MW (Da)
2.55
ALogP
6
HBA
3
HBD
112.8
PSA (Ų)
0.77
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | IC50 | 5.37 | 5.37 | 4300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | IC50 | = | 4300.0 | nM | 5.37 | Displacement of [3H]dichlorokynurenate ([3H]-DCKA) from N-methyl-D-aspartate glu... | 10882363 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10882363 | 10.1021/jm990957g | Glutamate NMDA receptor | 1 |
| 10882363 | 10.1021/jm990957g | Glutamate receptor ionotropic, AMPA | 1 |
| 10882363 | 10.1021/jm990957g | Mus musculus | 1 |
Data from ChEMBL 36 via Core Engine