Compound Detail
CHEMBL311325
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Basic Information
| ChEMBL ID | CHEMBL311325 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PCNPLBNJGWTEHA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
352.9
MW (Da)
4.55
ALogP
4
HBA
1
HBD
55.6
PSA (Ų)
0.40
QED
0
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 CHEMBL4317 | EC50 | 5.7 | 5.7 | 1995.3 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | EC50 | = | 1995.26 | nM | 5.7 | Compound was tested against 5-HT4 receptor through agonism of 5-HT mediated rela... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)80414-5 | 5-hydroxytryptamine receptor 4 | 1 |
Data from ChEMBL 36 via Core Engine