Compound Detail
CHEMBL3126108
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Basic Information
| ChEMBL ID | CHEMBL3126108 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AITVFSBTANYJCU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
386.9
MW (Da)
2.92
ALogP
6
HBA
1
HBD
74.0
PSA (Ų)
0.60
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 10.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 CHEMBL4317 | Ki | 10.15 | 10.15 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Ki | = | 0.07 | nM | 10.15 | Displacement of [3H]GR113808 from 5HT4 receptor in Sprague-Dawley rat striatal m... | 24157369 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24157369 | 10.1016/j.bmcl.2013.09.097 | 5-hydroxytryptamine receptor 4 | 1 |
Data from ChEMBL 36 via Core Engine