Compound Detail
CHEMBL3132887
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Basic Information
| ChEMBL ID | CHEMBL3132887 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XMHAGVWWGNNOTI-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
359.1
MW (Da)
2.49
ALogP
2
HBA
3
HBD
90.4
PSA (Ų)
0.73
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 6.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Uracil nucleotide/cysteinyl leukotriene receptor CHEMBL1075162 | EC50 | 6.15 | 6.15 | 708.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Uracil nucleotide/cysteinyl leukotriene receptor | EC50 | = | 715.0 | nM | 6.15 | Agonist activity at human GPR17 receptor transfected in 1321N1 astrocytoma cells... | - |
| Uracil nucleotide/cysteinyl leukotriene receptor | EC50 | = | 707.95 | nM | 6.15 | Agonist activity at recombinant human GPR17 short isoform transfected in human 1... | - |
| Uracil nucleotide/cysteinyl leukotriene receptor | EC50 | = | 707.95 | nM | 6.15 | Agonist activity at recombinant human GPR17 short isoform transfected in CHO cel... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C3MD00309D | Uracil nucleotide/cysteinyl leukotriene receptor | 1 |
Data from ChEMBL 36 via Core Engine