Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL3134255

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CC(C)C[C@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)OCc1ccccc1)C(=O)N[C@H](C=O)CCC(=O)N(C)C

Basic Information

ChEMBL ID CHEMBL3134255
Phase Preclinical
Structure Type MOL
InChI Key BZLBXSSNEWRFCY-PMVMPFDFSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

542.6
MW (Da)
1.33
ALogP
7
HBA
4
HBD
162.6
PSA (Ų)
0.25
QED
1
Ro5 Violations
15
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H38N6O6
MW 542.64
Aromatic Rings 2
Heavy Atoms 39
NP-Likeness -0.08

Activity Summary

Ki 1 meas. best 5.72

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Ki 5.72 5.72 1900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked Ki = 1900.0 nM 5.72 Inhibition of Norwalk virus recombinant His6-tagged protease using EDANS-EPDFHLQ... 24244836

Literature References

PubMed DOI Target Context # Activities
24244836 10.1039/c3md00219e Unchecked 1

Data from ChEMBL 36 via Core Engine