Compound Detail
CHEMBL314256
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL314256 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SAPCJZOHSAJPDX-SJORKVTESA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
278.4
MW (Da)
3.88
ALogP
3
HBA
1
HBD
24.4
PSA (Ų)
0.63
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate NMDA receptor CHEMBL1907608 | Ki | 6.07 | 6.07 | 843.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate NMDA receptor | Ki | = | 843.0 | nM | 6.07 | Tested for the inhibition of [3H]dizocilpine binding to N-methyl-D-aspartate (NM... | 8355251 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8355251 | 10.1021/jm00069a008 | Glutamate NMDA receptor | 2 |
Data from ChEMBL 36 via Core Engine