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Compound Detail

CHEMBL3142670

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CCCCCCCC[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C[C@H](C)C[C@H](O)CC(=O)CC)C(=O)N[C@@H](C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)NC(C)(C)C(=O)NC(C)C(=O)N[C@@H](C)CN(C)CCO)C(C)C

Basic Information

ChEMBL ID CHEMBL3142670
Phase Preclinical
Structure Type MOL
InChI Key QGHQNKRBPNIMLS-OGUNSEFRSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

1178.6
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C59H107N11O13
MW 1178.57

Activity Summary

IC50 1 meas. best 7.22

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Mus musculus
CHEMBL375
IC50 7.22 7.22 60.4 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Mus musculus IC50 = 60.4 nM 7.22 Inhibitory activity against the proliferation of lymphocytes in mouse allogenic ... 10617078

Literature References

PubMed DOI Target Context # Activities
10617078 10.1016/s0960-894x(99)00621-6 Mus musculus 2

Data from ChEMBL 36 via Core Engine