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Compound Detail

CHEMBL3142717

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CC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NC(C=O)CCC(=O)N(C)C

Basic Information

ChEMBL ID CHEMBL3142717
Phase Preclinical
Structure Type MOL
InChI Key GPAIWJUVOVJPDO-RRLUTRQMSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

413.5
MW (Da)
-1.93
ALogP
6
HBA
4
HBD
153.8
PSA (Ų)
0.29
QED
0
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H31N5O6
MW 413.48
Aromatic Rings 0
Heavy Atoms 29
NP-Likeness -0.04

Activity Summary

IC50 1 meas. best 6.47

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Human rhinovirus sp.
CHEMBL612470
IC50 6.47 6.47 340.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Human rhinovirus sp. IC50 = 340.0 nM 6.47 Antiviral activity against human rhinovirus-14 in HeLa cells -

Literature References

PubMed DOI Target Context # Activities
- 10.1016/S0960-894X(96)00537-9 Human rhinovirus sp. 1

Data from ChEMBL 36 via Core Engine