Compound Detail
CHEMBL314403
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Basic Information
| ChEMBL ID | CHEMBL314403 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VCQTVMUCIZQHEV-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
324.3
MW (Da)
-1.91
ALogP
8
HBA
6
HBD
134.8
PSA (Ų)
0.38
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Alpha-glucosidase CHEMBL2974 | IC50 | 4.62 | 4.62 | 23900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Alpha-glucosidase | IC50 | = | 23900.0 | nM | 4.62 | Inhibitory activity was determined against bovine liver beta galactosidase | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)80688-0 | Lysosomal alpha-glucosidase | 2 |
| - | 10.1016/S0960-894X(01)80688-0 | Lysosomal acid glucosylceramidase | 2 |
| - | 10.1016/S0960-894X(01)80688-0 | Alpha-glucosidase | 1 |
Data from ChEMBL 36 via Core Engine