Alpha-glucosidase · SINGLE PROTEIN · Bos taurus
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Structured disease, protein, and project context should read before the lower-level identity rail.
As of 2026-09-14Protein identity stays anchored to UniProt Q9MYM4. Use UniProt Q9MYM4 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9MYM4 as the stable identity anchor, then attach disease evidence before program review.
Lysosomal alpha-glucosidase
Review this target as Alpha-glucosidase, mapped to UniProt Q9MYM4. ChEMBL maps the protein component as Lysosomal alpha-glucosidase. Sequence length is 937 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Alpha-glucosidase as ChEMBL target CHEMBL2974, mapped to UniProt Q9MYM4. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Alpha-glucosidase |
| Target Type | SINGLE PROTEIN |
| Organism | Bos taurus |
| UniProt | Q9MYM4 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Lysosomal alpha-glucosidase |
| UniProt Accession | Q9MYM4 |
| Component Type | Protein |
| Sequence Length | 937 aa |
Lysosomal alpha-glucosidase
Review this target as Alpha-glucosidase, mapped to UniProt Q9MYM4. ChEMBL maps the protein component as Lysosomal alpha-glucosidase. Sequence length is 937 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL86865 | 6.62 | IC50 | 240.0 | Preclinical |
| CHEMBL307429 | 6.4 | IC50 | 400.0 | Clinical |
| CHEMBL86772 | 6.24 | IC50 | 571.0 | Preclinical |
| CHEMBL313375 | 5.52 | IC50 | 3000.0 | Preclinical |
| CHEMBL314403 | 4.62 | IC50 | 23900.0 | Preclinical |
| CHEMBL87120 | 4.33 | IC50 | 46900.0 | Preclinical |
| CHEMBL2114189 | 4.05 | IC50 | 89000.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 7 | 5.3 |
| tissue-based format | 2 | 5 | 5.0 |