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Compound Detail

CHEMBL3188458

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CC(C)=CCC/C(C)=C/CC/C(C)=C/C(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

Basic Information

ChEMBL ID CHEMBL3188458
Phase Preclinical
Structure Type MOL
InChI Key SBQAKZYUNWNIRL-WIPKXTQKSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

578.8
MW (Da)
6.53
ALogP
6
HBA
2
HBD
100.9
PSA (Ų)
0.17
QED
2
Ro5 Violations
10
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C36H50O6
MW 578.79
Aromatic Rings 0
Heavy Atoms 42
NP-Likeness 2.24

Activity Summary

IC50 2 meas. best 7.22

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 7.22 6.35 59.5 2

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine