Compound Detail
CHEMBL318882
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL318882 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZFINDMDDTBLULB-LSDHHAIUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
379.9
MW (Da)
3.61
ALogP
5
HBA
2
HBD
75.6
PSA (Ų)
0.80
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1D CHEMBL5450 | Ki | 7.8 | 7.8 | 15.8 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 1D | Ki | = | 15.85 | nM | 7.8 | Binding affinity to 5-hydroxytryptamine 1D receptor in the rat forebrain by [3H]... | 10021946 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10021946 | 10.1016/s0960-894x(98)00728-8 | 5-hydroxytryptamine receptor 1D | 3 |
Data from ChEMBL 36 via Core Engine