Compound Detail
CHEMBL319787
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Basic Information
| ChEMBL ID | CHEMBL319787 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PMTQDTHDVBZNMC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
409.5
MW (Da)
4.43
ALogP
4
HBA
1
HBD
56.0
PSA (Ų)
0.50
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C, PKC; classical CHEMBL2097168 | IC50 | 6.35 | 6.35 | 450.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C, PKC; classical | IC50 | = | 450.0 | nM | 6.35 | Inhibition of protein kinase C was evaluated as Inhibitory concentration | 8421286 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8421286 | 10.1021/jm00053a003 | Protein kinase C, PKC; classical | 1 |
| 8421286 | 10.1021/jm00053a003 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine