Compound Detail
CHEMBL3198390
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Basic Information
| ChEMBL ID | CHEMBL3198390 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IZMVXNJRIXIGGM-CUQLSPFUSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
251.3
MW (Da)
2.51
ALogP
3
HBA
1
HBD
54.4
PSA (Ų)
0.67
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.18
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Plasmodium falciparum CHEMBL364 | IC50 | 7.18 | 7.18 | 66.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Plasmodium falciparum | IC50 | = | 66.0 | nM | 7.18 | Antimalarial activity against Plasmodium falciparum RKL9 infected in human RBC a... | 33895706 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33895706 | 10.1016/j.bmc.2021.116159 | Plasmodium falciparum | 1 |
| 35985254 | 10.1016/j.ejmech.2022.114653 | Plasmodium falciparum | 1 |
Data from ChEMBL 36 via Core Engine