Compound Detail
CHEMBL321026
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL321026 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MSQUYQPJLHLJAK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
414.5
MW (Da)
5.52
ALogP
5
HBA
1
HBD
63.1
PSA (Ų)
0.26
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase CHEMBL247 | IC50 | 6.17 | 6.17 | 670.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase | IC50 | = | 670.0 | nM | 6.17 | Concentration required to protect the cell against HIV-1 strain IIIB viral cytop... | 15149669 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15149669 | 10.1016/j.bmcl.2004.04.008 | MT4 | 3 |
| 15149669 | 10.1016/j.bmcl.2004.04.008 | Human immunodeficiency virus type 1 reverse transcriptase | 2 |
Data from ChEMBL 36 via Core Engine