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Compound Detail

CHEMBL3211154

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C/C(=N\OC(=O)c1ccc(F)cc1)c1sc(-c2ccc(Cl)cc2)nc1C

Basic Information

ChEMBL ID CHEMBL3211154
Phase Preclinical
Structure Type MOL
InChI Key IAQYZTHTHVIENO-FSJBWODESA-N
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names

Molecular Properties

388.9
MW (Da)
5.49
ALogP
5
HBA
0
HBD
51.5
PSA (Ų)
0.34
QED
1
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H14ClFN2O2S
MW 388.85
Aromatic Rings 3
Heavy Atoms 26
NP-Likeness -1.81

Activity Summary

EC50 4 meas. best 6.91

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
EC50 6.91 6.6225 122.0 4

Activity Data Samples

Top measurements by pChEMBL value

Data from ChEMBL 36 via Core Engine