Compound Detail
CHEMBL321555
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Basic Information
| ChEMBL ID | CHEMBL321555 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZRLWYUNKZNRQLO-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
3.49
ALogP
6
HBA
0
HBD
67.1
PSA (Ų)
0.71
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.25
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Rattus norvegicus CHEMBL376 | IC50 | 4.25 | 4.225 | 56600.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Rattus norvegicus | IC50 | = | 56600.0 | nM | 4.25 | Inhibition of microsomal lipid peroxidation induced by CCl4/NADPH. | 7629818 |
| Rattus norvegicus | IC50 | = | 62600.0 | nM | 4.2 | Inhibition of microsomal lipid peroxidation induced by [Fe(3+)]-ADP/NADPH. | 7629818 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7629818 | 10.1021/jm00014a032 | Rattus norvegicus | 6 |
| 7629818 | 10.1021/jm00014a032 | Homo sapiens | 2 |
| 7629818 | 10.1021/jm00014a032 | Phospholipase A2, membrane associated | 1 |
| 15588081 | 10.1021/jm040810b | Telomerase reverse transcriptase | 1 |
Data from ChEMBL 36 via Core Engine