Compound Detail
CHEMBL3221571
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Basic Information
| ChEMBL ID | CHEMBL3221571 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AEOAISJQAMBBOS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
330.5
MW (Da)
3.34
ALogP
3
HBA
2
HBD
44.0
PSA (Ų)
0.80
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 CHEMBL4317 | Ki | 9.82 | 9.82 | 0.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Ki | = | 0.15 | nM | 9.82 | Displacement of [3H]GR113808 from 5-HT4 receptor in rat striatal membranes after... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C0MD00258E | 5-hydroxytryptamine receptor 4 | 1 |
Data from ChEMBL 36 via Core Engine