Compound Detail
CHEMBL3236273
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Basic Information
| ChEMBL ID | CHEMBL3236273 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | APZGOHLMCILMBL-ROUUACIJSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
465.3
MW (Da)
3.12
ALogP
3
HBA
0
HBD
64.4
PSA (Ų)
0.63
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prolyl endopeptidase CHEMBL2461 | Ki | 8.38 | 8.38 | 4.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prolyl endopeptidase | Ki | = | 4.2 | nM | 8.38 | Inhibition of porcine prolyl oligopeptidase using Z-Gly-Pro-AMC as substrate aft... | 24763264 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24763264 | 10.1016/j.ejmech.2014.04.014 | Prolyl endopeptidase | 1 |
Data from ChEMBL 36 via Core Engine