Compound Detail
CHEMBL324037
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Basic Information
| ChEMBL ID | CHEMBL324037 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UFDGFWYRIMJUBV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
227.3
MW (Da)
1.27
ALogP
4
HBA
3
HBD
81.1
PSA (Ų)
0.58
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.17
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| L1210 CHEMBL386 | IC50 | 4.17 | 4.17 | 67000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| L1210 | IC50 | = | 67000.0 | nM | 4.17 | Concentration required to inhibit the cell growth by 50 % after 48 hr in L1210 l... | 7658436 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7658436 | 10.1021/jm00018a009 | L1210 | 1 |
| 7658436 | 10.1021/jm00018a009 | A2780 | 1 |
Data from ChEMBL 36 via Core Engine