Compound Detail
CHEMBL3249366
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3249366 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MADUQKMQKQDWJH-UHFFFAOYSA-N |
| Parent Compound | CHEMBL266195 |
| Active Moiety | CHEMBL266195 |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
249.3
MW (Da)
2.15
ALogP
3
HBA
2
HBD
41.5
PSA (Ų)
0.69
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 2 meas. best 8.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Kd | 8.6 | 8.5 | 2.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Kd | = | 2.5 | nM | 8.6 | Displacement of (-)-[3H]dihydroalprenolol from beta adrenergic receptor in frog ... | 197238 |
| Unchecked | Kd | = | 4.0 | nM | 8.4 | Antagonist activity at beta adrenergic receptor in frog erythrocyte membrane ass... | 197238 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 197238 | 10.1021/jm00218a020 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine