Compound Detail
CHEMBL32861
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Basic Information
| ChEMBL ID | CHEMBL32861 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FZBTVVYNCSBSHI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
141.2
MW (Da)
0.37
ALogP
3
HBA
2
HBD
63.3
PSA (Ų)
0.55
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GABA-A receptor; anion channel CHEMBL1907607 | IC50 | 4.19 | 4.19 | 65000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GABA-A receptor; anion channel | IC50 | = | 65000.0 | nM | 4.19 | Displacement of [3H]GABA from Gamma-aminobutyric acid A (GABA-A) receptor in rat... | 2995665 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2995665 | 10.1021/jm00148a012 | GABA-A receptor; anion channel | 1 |
| 2995665 | 10.1021/jm00148a012 | GABA B receptor | 1 |
| 2995665 | 10.1021/jm00148a012 | Rattus norvegicus | 1 |
Data from ChEMBL 36 via Core Engine