Compound Detail
CHEMBL3288555
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3288555 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DEQMSMTUSGDCRS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
371.4
MW (Da)
4.26
ALogP
4
HBA
2
HBD
83.7
PSA (Ų)
0.56
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HT-29 CHEMBL384 | IC50 | 5.01 | 5.01 | 9700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HT-29 | IC50 | = | 9700.0 | nM | 5.01 | Inhibition of Wnt signaling in human HT29 cells assessed as inhibition of beta-c... | 24950489 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24950489 | 10.1016/j.ejmech.2014.05.071 | HT-29 | 9 |
| 24950489 | 10.1016/j.ejmech.2014.05.071 | LoVo | 1 |
| 24950489 | 10.1016/j.ejmech.2014.05.071 | HepG2 | 1 |
| 24950489 | 10.1016/j.ejmech.2014.05.071 | A549 | 1 |
Data from ChEMBL 36 via Core Engine