Compound Detail
CHEMBL3288970
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Basic Information
| ChEMBL ID | CHEMBL3288970 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UDHNPQBBLGONPJ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
282.2
MW (Da)
4.36
ALogP
3
HBA
1
HBD
55.2
PSA (Ų)
0.67
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.5
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Kinesin-like protein KIF11 CHEMBL4581 | IC50 | 5.5 | 5.5 | 3200.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Kinesin-like protein KIF11 | IC50 | = | 3200.0 | nM | 5.5 | Inhibition of C-terminal His-tagged KSP ATPase motor domain (unknown origin) exp... | 24794744 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24794744 | 10.1016/j.bmc.2014.04.008 | Kinesin-like protein KIF11 | 1 |
Data from ChEMBL 36 via Core Engine