Compound Detail
CHEMBL329300
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL329300 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YIMMEIRULOZLFI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
297.7
MW (Da)
2.70
ALogP
6
HBA
1
HBD
76.2
PSA (Ų)
0.58
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GABA-A receptor; anion channel CHEMBL1907607 | IC50 | 7.0 | 7.0 | 100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GABA-A receptor; anion channel | IC50 | = | 100.0 | nM | 7.0 | Displacement of [3H]- Diazepam from GABA-A Benzodiazepine receptor of rat forebr... | 1846920 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1846920 | 10.1021/jm00105a044 | GABA-A receptor; anion channel | 1 |
Data from ChEMBL 36 via Core Engine