Compound Detail
CHEMBL3298141
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Basic Information
| ChEMBL ID | CHEMBL3298141 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GTSKFZRBVBRULH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
266.3
MW (Da)
4.22
ALogP
3
HBA
1
HBD
38.1
PSA (Ų)
0.77
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily A member 5 CHEMBL4306 | IC50 | 6.11 | 6.11 | 784.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Potassium voltage-gated channel subfamily A member 5 | IC50 | = | 784.0 | nM | 6.11 | Inhibition of human Kv1.5 expressed in mouse L929 cells assessed as inhibition o... | 24881565 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24881565 | 10.1016/j.bmcl.2014.05.035 | Potassium voltage-gated channel subfamily A member 5 | 1 |
| 24881565 | 10.1016/j.bmcl.2014.05.035 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine