Compound Detail
CHEMBL330292
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Basic Information
| ChEMBL ID | CHEMBL330292 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HIJHZQHIPSBZTR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
321.4
MW (Da)
5.28
ALogP
2
HBA
1
HBD
52.5
PSA (Ų)
0.56
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.35
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 CHEMBL4825 | IC50 | 6.35 | 6.35 | 450.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 | IC50 | = | 450.0 | nM | 6.35 | Inhibitory potency evaluated against rat p38 kinase | 9873604 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9873604 | 10.1016/s0960-894x(98)00495-8 | Mitogen-activated protein kinase 14 | 1 |
Data from ChEMBL 36 via Core Engine