Compound Detail
CHEMBL331844
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Basic Information
| ChEMBL ID | CHEMBL331844 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PWNZHJZERWGNHA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
278.2
MW (Da)
1.01
ALogP
7
HBA
2
HBD
129.7
PSA (Ų)
0.63
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.04
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA CHEMBL2093871 | Ki | 6.04 | 6.04 | 910.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA | Ki | = | 910.0 | nM | 6.04 | Binding affinity for ionotropic glutamate receptor AMPA using [3H]AMPA as radiol... | 14505662 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14505662 | 10.1016/s0960-894x(03)00740-6 | Glutamate receptor ionotropic, AMPA | 1 |
Data from ChEMBL 36 via Core Engine