Compound Detail
CHEMBL3321797
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Basic Information
| ChEMBL ID | CHEMBL3321797 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BSBJKTRDMXTSGL-IFMALSPDSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
368.6
MW (Da)
5.04
ALogP
2
HBA
0
HBD
23.6
PSA (Ų)
0.60
QED
1
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | Ki | 7.21 | 7.21 | 62.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | Ki | = | 62.0 | nM | 7.21 | Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mi... | 25073094 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25073094 | 10.1021/jm500880c | 5-hydroxytryptamine receptor 1A | 1 |
| 25073094 | 10.1021/jm500880c | 5-hydroxytryptamine receptor 7 | 1 |
Data from ChEMBL 36 via Core Engine