Compound Detail
CHEMBL3327148
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3327148 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WDAIWFJRXVKXNS-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
242.6
MW (Da)
1.28
ALogP
4
HBA
3
HBD
99.0
PSA (Ų)
0.42
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase CHEMBL247 | IC50 | 5.82 | 5.82 | 1500.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus type 1 reverse transcriptase | IC50 | = | 1500.0 | nM | 5.82 | Inhibition of wild type HIV1 reverse transcriptase assessed as inhibition of DNA... | 25144111 |
| Human immunodeficiency virus type 1 reverse transcriptase | IC50 | = | 1500.0 | nM | 5.82 | Inhibition of HIV1 reverse transcriptase p66/p51 polymerase using PPT57 DNA/Cy5-... | 29478802 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25144111 | 10.1021/jm501010f | Human immunodeficiency virus type 1 reverse transcriptase | 1 |
| 29478802 | 10.1016/j.bmc.2018.02.017 | Human immunodeficiency virus type 1 reverse transcriptase | 1 |
Data from ChEMBL 36 via Core Engine