Compound Detail
CHEMBL332730
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Basic Information
| ChEMBL ID | CHEMBL332730 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZHROCCFQLIDXHR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
238.3
MW (Da)
3.18
ALogP
2
HBA
1
HBD
37.9
PSA (Ų)
0.76
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.86
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H3 receptor CHEMBL4124 | Ki | 6.86 | 6.86 | 137.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H3 receptor | Ki | = | 137.0 | nM | 6.86 | Rat Histamine H3 receptor antagonism determined by [K+] - evoked depolarization-... | 8809168 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8809168 | 10.1021/jm960138l | Histamine H3 receptor | 1 |
| 8809168 | 10.1021/jm960138l | Mus musculus | 1 |
Data from ChEMBL 36 via Core Engine