Compound Detail
CHEMBL333880
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Basic Information
| ChEMBL ID | CHEMBL333880 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | XPNTXELFGKOQDL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
352.5
MW (Da)
4.65
ALogP
5
HBA
0
HBD
42.7
PSA (Ų)
0.62
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL1800 | Ki | 7.82 | 7.82 | 15.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | Ki | = | 15.0 | nM | 7.82 | Binding affinity to the cloned human corticotropin releasing factor receptor 1 | 15203140 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15203140 | 10.1016/j.bmcl.2004.05.019 | Corticotropin-releasing factor receptor 1 | 1 |
| 15203140 | 10.1016/j.bmcl.2004.05.019 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine