Compound Detail
CHEMBL334101
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Basic Information
| ChEMBL ID | CHEMBL334101 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QLYLRFLMYPPPSP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
378.5
MW (Da)
3.60
ALogP
6
HBA
2
HBD
69.9
PSA (Ų)
0.38
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| L1210 CHEMBL386 | IC50 | 6.05 | 6.05 | 890.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| L1210 | IC50 | = | 890.0 | nM | 6.05 | In vitro inhibitory activity against murine L1210 leukemia | 1732555 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1732555 | 10.1021/jm00080a026 | L1210 | 2 |
| 1732555 | 10.1021/jm00080a026 | Mus musculus | 2 |
Data from ChEMBL 36 via Core Engine