Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL3350688

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
C=C1/C(=C/C=C2/CCC[C@]3(C)[C@@H]([C@H](C)C[C@@H]4C[C@@](C)(O)C(=O)N4C)CC[C@@H]23)C[C@@H](O)C[C@@H]1O

Basic Information

ChEMBL ID CHEMBL3350688
Phase Preclinical
Structure Type MOL
InChI Key YCKBNQNSQUFGRQ-HOYRRFRRSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

457.7
MW (Da)
4.14
ALogP
4
HBA
3
HBD
81.0
PSA (Ų)
0.59
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C28H43NO4
MW 457.66
Aromatic Rings 0
Heavy Atoms 33
NP-Likeness 2.27

Activity Summary

IC50 1 meas. best 7.3

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Vitamin D3 receptor
CHEMBL2353
IC50 7.3 7.3 50.0 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
15109656 10.1016/s0960-894x(04)00294-x Vitamin D3 receptor 1

Data from ChEMBL 36 via Core Engine