Compound Detail
CHEMBL336002
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Basic Information
| ChEMBL ID | CHEMBL336002 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SVHIOPOOPNXCLH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
303.3
MW (Da)
4.44
ALogP
3
HBA
0
HBD
30.7
PSA (Ų)
0.55
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 CHEMBL260 | IC50 | 7.01 | 7.01 | 98.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 14 | IC50 | = | 98.0 | nM | 7.01 | In vitro inhibitory concentration against Mitogen-activated protein kinase p38 a... | 14561090 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14561090 | 10.1021/jm0301787 | Mitogen-activated protein kinase 14 | 2 |
| 29706527 | 10.1016/j.bmc.2018.04.047 | Unchecked | 1 |
| 36538005 | 10.1021/acs.jmedchem.2c01599 | Serine/threonine-protein kinase D1 | 1 |
Data from ChEMBL 36 via Core Engine