Compound Detail
CHEMBL336017
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Basic Information
| ChEMBL ID | CHEMBL336017 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KAMOVQVEAFPAHG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
319.9
MW (Da)
2.57
ALogP
4
HBA
2
HBD
66.2
PSA (Ų)
0.78
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.89 | 5.89 | 1300.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 1300.0 | nM | 5.89 | Electrophysiological assays in Xenopus oocytes expressing cloned NMDA receptor (... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7473565 | 10.1021/jm00022a003 | Glutamate receptor ionotropic, NMDA 1 | 1 |
| 7473565 | 10.1021/jm00022a003 | Glutamate receptor ionotropic, AMPA | 1 |
| 7473565 | 10.1021/jm00022a003 | Unchecked | 1 |
| - | 10.1016/0960-894X(96)00036-4 | Glutamate receptor ionotropic, NMDA 1 | 1 |
| - | 10.1016/0960-894X(96)00036-4 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine