Compound Detail
CHEMBL3360931
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3360931 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UHXMMLUCQDVMRD-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
379.5
MW (Da)
4.71
ALogP
4
HBA
0
HBD
39.8
PSA (Ų)
0.45
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 CHEMBL216 | EC50 | 6.11 | 6.11 | 776.2 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | EC50 | = | 783.0 | nM | 6.11 | Positive allosteric modulator activity at human muscarinic receptor subtype 1 ex... | 25435150 |
| Muscarinic acetylcholine receptor M1 | EC50 | = | 776.25 | nM | 6.11 | Positive allosteric modulator activity at human muscarinic receptor subtype 1 ex... | 25435150 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25435150 | 10.1016/j.bmcl.2014.11.011 | Muscarinic acetylcholine receptor M1 | 3 |
Data from ChEMBL 36 via Core Engine