Compound Detail
CHEMBL3360950
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Basic Information
| ChEMBL ID | CHEMBL3360950 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LGSSOQROMRKPOR-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
459.6
MW (Da)
5.20
ALogP
6
HBA
0
HBD
57.6
PSA (Ų)
0.36
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 CHEMBL216 | EC50 | 5.94 | 5.94 | 1148.2 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M1 | EC50 | = | 1150.0 | nM | 5.94 | Positive allosteric modulator activity at human muscarinic receptor subtype 1 ex... | 25435150 |
| Muscarinic acetylcholine receptor M1 | EC50 | = | 1148.15 | nM | 5.94 | Positive allosteric modulator activity at human muscarinic receptor subtype 1 ex... | 25435150 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25435150 | 10.1016/j.bmcl.2014.11.011 | Muscarinic acetylcholine receptor M1 | 3 |
Data from ChEMBL 36 via Core Engine