Compound Detail
CHEMBL336632
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Basic Information
| ChEMBL ID | CHEMBL336632 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VMWVJPXQIMZLJG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
334.4
MW (Da)
1.83
ALogP
6
HBA
3
HBD
87.1
PSA (Ų)
0.47
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.53
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| L1210 CHEMBL386 | EC50 | 6.53 | 6.53 | 296.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| L1210 | EC50 | = | 296.0 | nM | 6.53 | Concentration of compound required to inhibit the cellular protein biosynthesis ... | 8421288 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8421288 | 10.1021/jm00053a005 | NADH-ubiquinone oxidoreductase chain 4 | 2 |
| 8421288 | 10.1021/jm00053a005 | P388 | 2 |
| 8421288 | 10.1021/jm00053a005 | ADMET | 2 |
| 8421288 | 10.1021/jm00053a005 | L1210 | 1 |
| 8421288 | 10.1021/jm00053a005 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine