Compound Detail
CHEMBL336923
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Basic Information
| ChEMBL ID | CHEMBL336923 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZGRQGEXXUUJWQS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
391.3
MW (Da)
2.91
ALogP
4
HBA
2
HBD
83.5
PSA (Ų)
0.62
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Sulfonylurea receptors; K-ATP channels CHEMBL2095152 | IC50 | 5.07 | 5.07 | 8600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Sulfonylurea receptors; K-ATP channels | IC50 | = | 8600.0 | nM | 5.07 | IC50 evaluated by measuring contraction and relaxation of guinea pig bladder str... | 8917648 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8917648 | 10.1021/jm960365n | Sulfonylurea receptors; K-ATP channels | 1 |
| - | 10.6019/CHEMBL3301361 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine